There is much we do not know about nanotechnology. Despite its tremendous promise, nanotechnology today is mostly forecast and fervent hope. Predictions that spending on nanotechnology will increase from current levels of $13 billion to more than $1 trillion by 2015 are no more than that – simply predictions. Hopes that nanotechnology will be an essential part of solving the globe's energy, food, and water problems should be tempered by recalling a century of revolutionary technologies that failed to live up (...) to their early promise such as nuclear energy, supersonic airplanes, or gene therapy. Many other questions continue to nip at nanotechnology's heels, not the least of which are debates about what is and is not technically feasible. Despite these uncertainties, we can have complete confidence in one aspect of nanotechnology's future – it will be subject to a host of regulations. (shrink)

Risk management of nanotechnology is challenged by the enormous uncertainties about the risks, benefits, properties, and future direction of nanotechnology applications. Because of these uncertainties, traditional risk management principles such as acceptable risk, cost–benefit analysis, and feasibility are unworkable, as is the newest risk management principle, the precautionary principle. Yet, simply waiting for these uncertainties to be resolved before undertaking risk management efforts would not be prudent, in part because of the growing public concerns about nanotechnology driven by risk perception (...) heuristics such as affect and availability. A more reflexive, incremental, and cooperative risk management approach is required, which not only will help manage emerging risks from nanotechnology applications, but will also create a new risk management model for managing future emerging technologies. (shrink)

Nanotechnology is the latest in a growing list of emerging technologies that includes nuclear technologies, genetics, reproductive biology, biotechnology, information technology, robotics, communication technologies, surveillance technologies, synthetic biology, and neuroscience. As was the case for many of the technologies that came before, a key question facing nanotechnology is what type of regulatory oversight is appropriate for this emerging technology. As two of us wrote several years ago, the question facing nanotechnology is not whether it will be regulated, but when and (...) how.Yet, appropriate regulation of nanotechnology will be challenging. The term “nanotechnology” incorporates a broad, diverse range of materials, technologies, and products, with an even greater spectrum of potential risks and benefits. This technology slashes across the jurisdiction of many existing regulatory statutes and regulatory agencies, and does so across the globe. Nanotechnology is developing at an enormously rapid rate, perhaps surpassing the capability of any potential regulatory framework to keep pace. Finally, the risks of nanotechnology remain largely unknown, both because of the multitude of variations in the technology and because of the limited applicability of traditional toxicological approaches such as structure-activity relationship to nanotechnology products. (shrink)

xs1F61ς … xs22EFξειργxs22EFσατο of MSS. is generally corrected to the third person plural, but it would be more like Thucydides to xs22EFξεxs22EFργαστο write: this would then be another instance of the corruption of pluperfects, such as S000983880001956X_inline1 into xs1F20γγxs22EFλλετο and the like, of which many instances are given by Cobet in Nov. Lect. 422, Var. Lect. 253. In the old edition of Poppo, 1826, vol. ii. pt. ii. p. 297, xs22EFξxs22EFπγαστο is given as contained in Cod. Bas. ex emend., but (...) it is not noticed by Poppo-Stahl or recent editors. Ως with the pluperfect is Thucydidean: Mr. Marchant on ii. 59 refers to iii. 23, 1; 26, 4; 27, 1; 69, 2. See the remarks of Poppo in vol. i. part ii. p. 44 sq. on this MS. (shrink)

Sleep researchers in different disciplines disagree about how fully dreaming can be explained in terms of brain physiology. Debate has focused on whether REM sleep dreaming is qualitatively different from nonREM (NREM) sleep and waking. A review of psychophysiological studies shows clear quantitative differences between REM and NREM mentation and between REM and waking mentation. Recent neuroimaging and neurophysiological studies also differentiate REM, NREM, and waking in features with phenomenological implications. Both evidence and theory suggest that there are isomorphisms between (...) the phenomenology and the physiology of dreams. We present a three-dimensional model with specific examples from normally and abnormally changing conscious states. Key Words: consciousness; dreaming; neuroimaging; neuromodulation; NREM; phenomenology; qualia; REM; sleep. (shrink)

Trust is a topic of longstanding philosophical interest. It is indispensable to every kind of coordinated human activity, from sport to scientific research. Even more, trust is necessary for the successful dissemination of knowledge, and by extension, for nearly any form of practical deliberation and planning. Without trust, we could achieve few of our goals and would know very little. Despite trust’s fundamental importance in human life, there is substantial philosophical disagreement about what trust is, and further, how trusting is (...) normatively constrained and best theorized about in relation to other things we value. This entry is divided into three sections, which explore key (and sometimes interconnected) ethical and epistemological themes in the philosophy of trust: (1) The Nature of Trust; (2) The Normativity of Trust, and (3) The Value of Trust. (shrink)

This paper challenges defenders/advocates of the semantic-completeness route towards gluts to explain, in simple and plausible terms, why the ‘trivializer paradox’, framed in terms of closure relatives on theories, fails to undermine their argument.

This paper represents an attempt to clarify a number of long-standing issues concerning the nature and status of the special and general principles of relativity in particular and symmetry or invariance principles in general. An analysis of the active and passive interpretations of symmetry operations is offered. This analysis yields an evaluation of the old covariance-invariance issue. It also demonstrates that the passive interpretation, insofar as it is not trivial, is parasitic on the active picture. Finally, the analysis shows that (...) grave difficulties lie in the way of any attempt to generalize the special principle of relativity in a manner like the one Einstein originally proposed. (shrink)

Anselm's argument has two distinct conclusions: (a) we cannot intelligibly doubt that god exists, and (b) this god, whose existence we cannot doubt, exists necessarily. if we replace anselm's vague conception of god by the spinozistic conception of substance, a defensible version of the ontological argument, understood as having these two conclusions, can be constructed. two important consequences of this analysis are: (1) the ontological argument, properly understood, deals simply with the concept of substance. it is a further question whether (...) substance ought to be understood as god. (2) the ontological argument does not actually demonstrate the existence of anything. it simply makes clear the consequences of adopting a metaphysical view which employs the spinozistic conception of substance. (shrink)

How are dependent (or linked) premises to be distinguished from independent (or convergent) premises? Deductive validity, sometimes proposed as a necessary condition for depende'nce, cannot be, for the premises of both inductive and deductive but invalid arguments can be dependent. The question is really this: When do multiple premises for a certain conclusion fonn one argument for that conclusion and when do they form multiple arguments? Answer: Premises are dependent when the evidence they offer for their conclusion is more than (...) the ordinary sum of their probabilities. Ordinary sums are defined in the paper. (shrink)

A central argument for the view that God's necessary omniscience [( Bgf p )] precludes freewill is unsound, because the necessity of the consequence is not the necessity of the consequent, and nor is Bgf true. God's belief in some particular proposition f about what I will do is not necessary, as I might do something that makes ~ f true. Fischer and Tognazzini claim that this counterargument argument assumes that I must freely do the something that makes f true. (...) But plainly it doesn't. All that it assumes is that I will do the something that makes f true. It makes no difference whether I do that thing unfreely, or "deterministicall". The argument does not assume the existence of a case of freewill in the face of divine foreknowledge, but instead considers the necessity of God's belief in some particular designated proposition f. The argument does not depend, as Fischer and Tognazzini suppose, on whether God's knowledge is a function of the facts (omniscience) or vice versa (infallibility). (shrink)

With an intellectual autobiography by Hans J. Morgenthau.

The meaning of valid proxy consent for children has recently been the subject of an important debate between Richard McCormick and Paul Ramsey on the ethics of experimenting with children. Ramsey is willing to agree with McCormick that parental consent for a child to undergo some medical procedure is valid only if parents consider what the child would consent to if he could. But beyond this, Ramsey has a fundamentally different conception of the child from McCormick, and therefore gives a (...) very different interpretation to this standard for valid proxy consent. In Ramsey's view, McCormick's basic mistake is to think of the child as a small adult, thereby overlooking the child's peculiar vulnerabilities and needs. In particular, McCormick fails to attend to the child's needs for "preservation in life and healthful growth". In this paper, the author pursues Ramsey's suggestion that a correct analysis of valid proxy consent for children would replace the "language of consent" with the "language of need". He does this by sketching a theory of parenthood that rests on two central notions: that of primary goods, as found in the writing of John Rawls, and that of autonomy. (shrink)

We show that if the weak compactness of a cardinal is made indestructible by means of any preparatory forcing of a certain general type, including any forcing naively resembling the Laver preparation, then the cardinal was originally supercompact. We then apply this theorem to show that the hypothesis of supercompactness is necessary for certain proof schemata.

In his book SEXUAL DESIRE, Roger Scruton wrongly maintains that human sexual experience is essential intentional. His thesis depends on his highly revisionary definition of 'sexual desire', the artificial nature of which I expose and criticise. He admits that homosexual desire is capable of the same kind of intentionality as heterosexual desire, and is therefore not intrinsically obscene or perverted, but he advances reasons why homosexuality is morally different from heterosexuality and is therefore an object of disapproval. His arguments presuppose (...) 'an impassable moral divide' between the sexes, and are, on his own admission, not very cogent. Since he allows that homosexual desire is a natural and spontaneous phenomenon and also proposes that moral education should guide us towards a state in which our sexuality is entirely integrated within a life of personal affection and responsibility, consistency requires that he adopt a sexual ideology which does not discriminate against homosexuality. For homosexuals are unlikely to achieve the 'sexual integrity' which Scruton advocates (and which I endorse) if they are constantly encouraged to disparage their own sexual nature and if social institutions make no positive provision for them. (shrink)

This article argues that time-asymmetric processes in spacetime are enantiomorphs. Subsequently, the Kantian puzzle concerning enantiomorphs in space is reviewed to introduce a number of positions concerning enantiomorphy, and to arrive at a dilemma: one must either reject that orientations of enantiomorphs are determinate, or furnish space or objects with orientation. The discussion on space is then used to derive two problems in the debate on the direction of time. First, it is shown that certain kinds of reductionism about the (...) direction of time are at variance with the claim that orientation of enantiomorphic objects is intrinsic. Second, it is argued that reductive explanations of time-asymmetric processes presuppose that enantiomorphic processes do not have determinate orientation. (shrink)

Shows that the Western tradition of statecraft, long considered the method of tyrants and oligarchs, can steer our thinking about democracy in bold new directions.